The Effect of The Ethanolic Extract of The Leaf of Chromolaena odorata on The Packed Cell Volume (PCV) of Wistar Albino Rats.

CHIKE SAMUEL OKAFOR, ARINZE CYPRAIN UGOCHUKWU, KINGSLEY IFEANYI UBAOJI, OKWUOMA HELEN NNABUENYI, NKECHI CLARA OKAFOR

Abstract


Abstract

The study investigated the hematinic effect of the ethanolic extract of Chromolaena odorata leaf on groups of male wistar albino rats. The rats were divided into 3 groups of 5 rats each .Group A and B which were the treated groups received 10mg/kg and 20mg/kg body weight of the extract .Group C (control) was given 5% solution of tween 80 only. The administration of the extract was done orally for a total period of 21 days .Blood samples were collected at the end of the study and the results of the blood samples analysis showed that group A and B had mean PCV levels of 29±0.01% and 31±0.09% respectively while that of group C (control) was 32±0.17% .The was no significant difference (P>0.05) between the treated and non-treated groups . The results of the study showed that the ethanolic extract of Chromolaena odorata leaf had no adverse effect on the packed cell volume (PCV) of the experimental rats.


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ISSN : 2251-1563